| Protein Name | palmitoyl-protein thioesterase 1 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 19063 |
| Gene Symbol | Ppt1 |
| UniProt | O88531 (PPT1_MOUSE), Q3U6J9 (Q3U6J9_MOUSE), Q3U6W3 (Q3U6W3_MOUSE), Q3TEL0 (Q3TEL0_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
81
Total Number of Articles : 58 |
Description |
palmitoyl-protein thioesterase 1 |
| Gene Summary |
Enables palmitoyl-(protein) hydrolase activity and phospholipase A2 inhibitor activity. Acts upstream of or within several processes, including grooming behavior; protein depalmitoylation; and visual perception. Located in several cellular components, including dendrite; lysosome; and neuronal cell body. Is active in presynaptic cytosol and synaptic vesicle membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Used to study neuronal ceroid lipofuscinosis 1 and neuronal ceroid lipofuscinosis 3. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 1. Orthologous to human PPT1 (palmitoyl-protein thioesterase 1). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |