Protein Name unc-13 homolog B
Organism Mus musculus
Gene ID 22249
Gene Symbol

Unc13b

UniProt Q9Z1N9 (UN13B_MOUSE), E9Q263 (E9Q263_MOUSE), A0A140LHX5 (A0A140LHX5_MOUSE)
Relationships Total Number of functionally related compound(s) : 15
Total Number of Articles : 15
Description

unc-13 homolog B

Gene Summary

Predicted to enable GTP-dependent protein binding activity; calmodulin binding activity; and syntaxin-1 binding activity. Involved in several processes, including negative regulation of synaptic plasticity; positive regulation of defense response to bacterium; and synaptic vesicle exocytosis. Acts upstream of or within several processes, including chemical synaptic transmission; innervation; and regulation of short-term neuronal synaptic plasticity. Located in several cellular components, including calyx of Held; early phagosome; and glutamatergic synapse. Is active in hippocampal mossy fiber to CA3 synapse. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and respiratory system. Orthologous to human UNC13B (unc-13 homolog B). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • protein unc-13 homolog B
  • UNC-13 homolog 1
  • munc13
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Properties