| Protein Name | vault RNA 2-1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 100126299 |
| Gene Symbol | VTRNA2-1 |
| UniProt | - |
| Relationships |
Total Number of functionally related compound(s) :
17
Total Number of Articles : 14 |
Description |
vault RNA 2-1 |
| Gene Summary |
This gene produces an RNA polymerase III transcript that resembles both a component of the ribonucleoprotein vault particle and a pre-microRNA. However, the RNA product does not function as a vault or microRNA; rather, it acts as a direct inhibitor of protein kinase R (also known as eukaryotic translation initiation factor 2-alpha kinase 2, EIF2AK2), and thereby plays an important role in the regulation of cell growth. This gene is located in the vicinity of a differentially methylated region (DMR) and is imprinted and may show allele-specific expression. This gene is also often hypermethylated and repressed in cancers. [provided by RefSeq, Nov 2015] |
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