Protein Name Cyclic-AMP response element binding protein A
Organism Drosophila melanogaster
Gene ID 39682
Gene Symbol

CrebA

UniProt P29747 (CREBA_DROME), Q1LZ07 (Q1LZ07_DROME)
Relationships Total Number of functionally related compound(s) : 24
Total Number of Articles : 42
Description

Cyclic-AMP response element binding protein A

Gene Summary

Enables DNA-binding transcription factor activity; chromatin binding activity; and cis-regulatory region sequence-specific DNA binding activity. Involved in regionalization; regulation of DNA-templated transcription; and salivary gland development. Located in chromatin and nucleolus. Part of transcription regulator complex. Is active in mitochondrial nucleoid. Is expressed in several structures, including adult brain; adult optic lobe; epithelium; gland; and gut section. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 16. Orthologous to human CREB3L1 (cAMP responsive element binding protein 3 like 1) and CREB3L2 (cAMP responsive element binding protein 3 like 2). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • Cyclic-AMP response element binding protein A
  • Box B-binding factor 2
  • CG7450-PA
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Properties