| Protein Name | IQ motif containing GTPase activating protein 1 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 29875 |
| Gene Symbol | Iqgap1 |
| UniProt | Q9JKF1 (IQGA1_MOUSE), Q3TPD2 (Q3TPD2_MOUSE), Q3TU98 (Q3TU98_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
24
Total Number of Articles : 23 |
Description |
IQ motif containing GTPase activating protein 1 |
| Gene Summary |
Enables small GTPase binding activity. Involved in cellular response to growth factor stimulus; positive regulation of protein kinase activity; and transmembrane receptor protein tyrosine kinase signaling pathway. Acts upstream of or within fibroblast migration; negative regulation of dephosphorylation; and regulation of cytokine production. Located in several cellular components, including cortical actin cytoskeleton; focal adhesion; and lateral plasma membrane. Part of ribonucleoprotein complex. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and skin. Orthologous to human IQGAP1 (IQ motif containing GTPase activating protein 1). [provided by Alliance of Genome Resources, Apr 2022] |
| synonyms |
|
| Properties | |