Protein Name protein inhibitor of activated STAT 1
Organism Mus musculus
Gene ID 56469
Gene Symbol

Pias1

UniProt O88907 (PIAS1_MOUSE), Q2M4G9 (Q2M4G9_MOUSE)
Relationships Total Number of functionally related compound(s) : 18
Total Number of Articles : 19
Description

protein inhibitor of activated STAT 1

Gene Summary

Enables several functions, including SUMO ligase activity; transcription cis-regulatory region binding activity; and ubiquitin protein ligase binding activity. Involved in several processes, including fat cell differentiation; protein sumoylation; and regulation of primary metabolic process. Located in nuclear periphery. Is active in several cellular components, including glutamatergic synapse; postsynaptic cytosol; and presynaptic cytosol. Colocalizes with PML body. Is expressed in several structures, including branchial arch; central nervous system; genitourinary system; sensory organ; and trunk mesenchyme. Orthologous to human PIAS1 (protein inhibitor of activated STAT 1). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • E3 SUMO-protein ligase PIAS1
  • DEAD/H (Asp-Glu-Ala-Asp/His) box binding protein 1
  • DEAD/H box-binding protein 1
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Properties