| Protein Name | EGFR pathway substrate 8, signaling adaptor |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 312812 |
| Gene Symbol | Eps8 |
| UniProt | F1M3L7 (EPS8_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
4
Total Number of Articles : 4 |
Description |
EGFR pathway substrate 8, signaling adaptor |
| Gene Summary |
Predicted to enable actin binding activity and small GTPase binding activity. Predicted to be involved in several processes, including actin filament organization; barbed-end actin filament capping; and small GTPase-mediated signal transduction. Predicted to act upstream of or within several processes, including adult locomotory behavior; behavioral response to ethanol; and cellular response to leukemia inhibitory factor. Is active in glutamatergic synapse and postsynaptic density. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 102. Orthologous to human EPS8 (EGFR pathway substrate 8, signaling adaptor). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |