Protein Name | protein kinase MEC1 |
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Organism | Saccharomyces cerevisiae S288C |
Gene ID | 852433 |
Gene Symbol | MEC1 |
UniProt | P38111 (ATR_YEAST) |
Relationships |
Total Number of functionally related compound(s) :
51
Total Number of Articles : 77 |
Description |
protein kinase MEC1 |
Gene Summary |
Enables protein kinase activity. Involved in DNA metabolic process; positive regulation of DNA-templated DNA replication; and signal transduction in response to DNA damage. Located in nucleus. Used to study several diseases, including Seckel syndrome; ataxia telangiectasia; colon cancer; endometrial cancer; and non-Hodgkin lymphoma. Human ortholog(s) of this gene implicated in Seckel syndrome (multiple); gastrointestinal system cancer (multiple); lung cancer; and pancreatic cancer. Orthologous to human ATR (ATR serine/threonine kinase). [provided by Alliance of Genome Resources, Jun 2025] |
synonyms |
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Properties | |