Protein Name protein kinase MEC1
Organism Saccharomyces cerevisiae S288C
Gene ID 852433
Gene Symbol

MEC1

UniProt P38111 (ATR_YEAST)
Relationships Total Number of functionally related compound(s) : 51
Total Number of Articles : 77
Description

protein kinase MEC1

Gene Summary

Enables protein kinase activity. Involved in DNA metabolic process; positive regulation of DNA-templated DNA replication; and signal transduction in response to DNA damage. Located in nucleus. Used to study several diseases, including Seckel syndrome; ataxia telangiectasia; colon cancer; endometrial cancer; and non-Hodgkin lymphoma. Human ortholog(s) of this gene implicated in Seckel syndrome (multiple); gastrointestinal system cancer (multiple); lung cancer; and pancreatic cancer. Orthologous to human ATR (ATR serine/threonine kinase). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • protein kinase MEC1
  • YBR136W
  • ESR1
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Properties