| Protein Name | Breast cancer type 1 susceptibility protein homolog;RING-type E3 ubiquitin transferase BRCA1 |
|---|---|
| Organism | Caenorhabditis elegans |
| Gene ID | 175499 |
| Gene Symbol | brc-1 |
| UniProt | B6VQ60 (BRCA1_CAEEL) |
| Relationships |
Total Number of functionally related compound(s) :
6
Total Number of Articles : 5 |
Description |
Breast cancer type 1 susceptibility protein homolog;RING-type E3 ubiquitin transferase BRCA1 |
| Gene Summary |
Enables ubiquitin protein ligase activity. Involved in several processes, including DNA repair; cellular response to ionizing radiation; and nuclear division. Part of BRCA1-BARD1 complex. Is expressed in germ line. Human ortholog(s) of this gene implicated in several diseases, including breast cancer (multiple); cervix uteri carcinoma in situ; gastrointestinal system cancer (multiple); hereditary breast ovarian cancer syndrome; and reproductive organ cancer (multiple). Orthologous to human BRCA1 (BRCA1 DNA repair associated). [provided by Alliance of Genome Resources, Apr 2022] |
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