| Protein Name | C-terminal binding protein 1 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 13016 |
| Gene Symbol | Ctbp1 |
| UniProt | O88712 (CTBP1_MOUSE), A0A0J9YU62 (A0A0J9YU62_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
24
Total Number of Articles : 15 |
Description |
C-terminal binding protein 1 |
| Gene Summary |
Enables RNA polymerase II-specific DNA-binding transcription factor binding activity; chromatin binding activity; and lncRNA binding activity. Involved in negative regulation of DNA-templated transcription; synaptic vesicle cycle; and white fat cell differentiation. Acts upstream of or within Notch signaling pathway and negative regulation of transcription by RNA polymerase II. Located in nucleus. Part of transcription repressor complex. Is active in GABA-ergic synapse; glutamatergic synapse; and presynaptic active zone cytoplasmic component. Is expressed in several structures, including central nervous system; chorionic plate; genitourinary system; limb; and lung. Orthologous to human CTBP1 (C-terminal binding protein 1). [provided by Alliance of Genome Resources, Jul 2025] |
| synonyms |
|
| Properties | |