Protein Name heat shock protein family B (small) member 8
Organism Rattus norvegicus
Gene ID 113906
Gene Symbol

Hspb8

UniProt Q9EPX0 (HSPB8_RAT)
Relationships Total Number of functionally related compound(s) : 11
Total Number of Articles : 9
Description

heat shock protein family B (small) member 8

Gene Summary

Predicted to enable protein homodimerization activity. Predicted to be involved in cellular response to unfolded protein and positive regulation of aggrephagy. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of protein folding chaperone complex. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2L; autosomal dominant distal hereditary motor neuronopathy 2; and myofibrillar myopathy 13 with rimmed vacuoles. Orthologous to human HSPB8 (heat shock protein family B (small) member 8). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • heat shock protein beta-8
  • alpha-crystallin C chain
  • crystallin, alpha C
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Properties