| Protein Name | CD70 molecule |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 970 |
| Gene Symbol | CD70 |
| UniProt | P32970 (CD70_HUMAN), A0A0U5JA32 (A0A0U5JA32_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
50
Total Number of Articles : 57 |
Description |
CD70 molecule |
| Gene Summary |
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008] |
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