| Protein Name | collagen type III alpha 1 chain |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 84032 |
| Gene Symbol | Col3a1 |
| UniProt | P13941 (CO3A1_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
22
Total Number of Articles : 22 |
Description |
collagen type III alpha 1 chain |
| Gene Summary |
Predicted to enable several functions, including integrin binding activity; platelet-derived growth factor binding activity; and protease binding activity. Predicted to be an extracellular matrix structural constituent conferring tensile strength. Involved in response to mechanical stimulus and skeletal system development. Located in extracellular matrix. Biomarker of several diseases, including bladder neck obstruction; glomerulosclerosis; obesity; rheumatic heart disease; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome; Ehlers-Danlos syndrome hypermobility type; end stage renal disease; and vascular type Ehlers-Danlos syndrome. Orthologous to human COL3A1 (collagen type III alpha 1 chain). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |