Protein Name KLF transcription factor 4
Organism Rattus norvegicus
Gene ID 114505
Gene Symbol

Klf4

UniProt Q923V7 (Q923V7_RAT)
Relationships Total Number of functionally related compound(s) : 59
Total Number of Articles : 50
Description

KLF transcription factor 4

Gene Summary

Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; histone deacetylase binding activity; and phosphatidylinositol 3-kinase regulator activity. Involved in several processes, including cellular response to endothelin; negative regulation of intracellular signal transduction; and regulation of DNA-templated transcription. Located in chromatin. Part of transcription regulator complex. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Orthologous to human KLF4 (KLF transcription factor 4). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • Krueppel-like factor 4
  • Kruppel like factor 4
  • Kruppel-like factor 4 (gut)
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Properties