Protein Name | KLF transcription factor 4 |
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Organism | Rattus norvegicus |
Gene ID | 114505 |
Gene Symbol | Klf4 |
UniProt | Q923V7 (Q923V7_RAT) |
Relationships |
Total Number of functionally related compound(s) :
59
Total Number of Articles : 50 |
Description |
KLF transcription factor 4 |
Gene Summary |
Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; histone deacetylase binding activity; and phosphatidylinositol 3-kinase regulator activity. Involved in several processes, including cellular response to organonitrogen compound; negative regulation of intracellular signal transduction; and regulation of transcription, DNA-templated. Located in chromatin and nucleus. Part of transcription regulator complex. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Orthologous to human KLF4 (Kruppel like factor 4). [provided by Alliance of Genome Resources, Apr 2022] |
synonyms |
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Properties | |