Protein Name THUMP domain 2 tRNA and snRNA guanosine methyltransferase
Organism Homo sapiens
Gene ID 80745
Gene Symbol

THUMPD2

UniProt Q9BTF0 (THUM2_HUMAN), Q969Z2 (Q969Z2_HUMAN), B4DP37 (B4DP37_HUMAN)
Relationships Total Number of functionally related compound(s) : 9
Total Number of Articles : 7
Description

THUMP domain 2 tRNA and snRNA guanosine methyltransferase

Gene Summary

Enables U6 snRNA (guanine-N(2))-methyltransferase activity. Involved in regulation of alternative mRNA splicing, via spliceosome. Part of tRNA methyltransferase complex. Is active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • U6 snRNA (guanine-N(2))-methyltransferase THUMPD2
  • THUMP domain-containing protein 2
  • SAM-dependent methyltransferase
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Properties