Protein Name ST3 beta-galactoside alpha-2,3-sialyltransferase 6
Organism Homo sapiens
Gene ID 10402
Gene Symbol

ST3GAL6

UniProt Q9Y274 (SIA10_HUMAN), A0A087WXB8 (A0A087WXB8_HUMAN)
Relationships Total Number of functionally related compound(s) : 13
Total Number of Articles : 9
Description

ST3 beta-galactoside alpha-2,3-sialyltransferase 6

Gene Summary

The protein encoded by this gene is a member of the sialyltransferase family. Members of this family are enzymes that transfer sialic acid from the activated cytidine 5'-monophospho-N-acetylneuraminic acid to terminal positions on sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins. This protein has high specificity for neolactotetraosylceramide and neolactohexaosylceramide as glycolipid substrates and may contribute to the formation of selectin ligands and sialyl Lewis X, a carbohydrate important for cell-to-cell recognition and a blood group antigen. [provided by RefSeq, Apr 2016]

synonyms
  • type 2 lactosamine alpha-2,3-sialyltransferase
  • CMP-NeuAc:beta-galactoside alpha-2,3-sialyltransferase VI
  • alpha2,3-sialyltransferase ST3Gal VI
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Properties