Protein Name C-C motif chemokine receptor 5
Organism Mus musculus
Gene ID 12774
Gene Symbol

Ccr5

UniProt P51682 (CCR5_MOUSE)
Relationships Total Number of functionally related compound(s) : 135
Total Number of Articles : 139
Description

C-C motif chemokine receptor 5

Gene Summary

Enables C-C chemokine binding activity and C-C chemokine receptor activity. Involved in negative regulation of macrophage apoptotic process. Acts upstream of or within defense response. Located in external side of plasma membrane. Is expressed in several structures, including alimentary system; brain; hemolymphoid system gland; liver and biliary system; and reproductive system. Used to study Coronavirus infectious disease. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; West Nile fever; autoimmune disease (multiple); berylliosis; and sarcoidosis (multiple). Orthologous to human CCR5 (C-C motif chemokine receptor 5). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • C-C chemokine receptor type 5
  • C-C CKR-5
  • CC-CKR-5
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Properties