Protein Name cysteine and glycine-rich protein 3
Organism Mus musculus
Gene ID 13009
Gene Symbol

Csrp3

UniProt P50462 (CSRP3_MOUSE), Q545C7 (Q545C7_MOUSE)
Relationships Total Number of functionally related compound(s) : 32
Total Number of Articles : 20
Description

cysteine and glycine-rich protein 3

Gene Summary

Enables actinin binding activity and telethonin binding activity. A structural constituent of muscle. Involved in several processes, including cardiac muscle contraction; detection of muscle stretch; and myofibril assembly. Acts upstream of or within several processes, including T-tubule organization; insulin receptor signaling pathway; and muscle cell cellular homeostasis. Located in Z disc. Is expressed in several structures, including genitourinary system; great vessel of heart; heart; limb segment; and skeletal musculature. Used to study congestive heart failure; dilated cardiomyopathy 1M; hypertrophic cardiomyopathy; and hypertrophic cardiomyopathy 12. Human ortholog(s) of this gene implicated in dilated cardiomyopathy; dilated cardiomyopathy 1M; hypertrophic cardiomyopathy; and hypertrophic cardiomyopathy 12. Orthologous to human CSRP3 (cysteine and glycine rich protein 3). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • cysteine and glycine-rich protein 3
  • LIM domain protein, cardiac
  • cardiac LIM protein
Click to show/hide the synonyms
Properties