Protein Name prolyl 4-hydroxylase, transmembrane
Organism Homo sapiens
Gene ID 54681
Gene Symbol

P4HTM

UniProt Q9NXG6 (P4HTM_HUMAN)
Relationships Total Number of functionally related compound(s) : 203
Total Number of Articles : 142
Description

prolyl 4-hydroxylase, transmembrane

Gene Summary

The product of this gene belongs to the family of prolyl 4-hydroxylases. This protein is a prolyl hydroxylase that may be involved in the degradation of hypoxia-inducible transcription factors under normoxia. It plays a role in adaptation to hypoxia and may be related to cellular oxygen sensing. Alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

synonyms
  • transmembrane prolyl 4-hydroxylase
  • HIF-PH4
  • HIF-prolyl hydroxylase 4
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Properties