Protein Name bradykinin receptor B2
Organism Rattus norvegicus
Gene ID 25245
Gene Symbol

Bdkrb2

UniProt P25023 (BKRB2_RAT), A0A0H2UI29 (A0A0H2UI29_RAT), G3V942 (G3V942_RAT)
Relationships Total Number of functionally related compound(s) : 55
Total Number of Articles : 35
Description

bradykinin receptor B2

Gene Summary

Enables beta-2 adrenergic receptor binding activity and bradykinin receptor activity. Involved in several processes, including acute inflammatory response to antigenic stimulus; cellular response to hypoxia; and maintenance of blood-brain barrier. Located in plasma membrane. Used to study several diseases, including asthma; pancreatitis; pleurisy; portal hypertension; and pulmonary hypertension. Biomarker of high grade glioma; hypertension; myocardial infarction; and sciatic neuropathy. Human ortholog(s) of this gene implicated in asthma; chronic obstructive pulmonary disease; hypertension; and rhinitis. Orthologous to human BDKRB2 (bradykinin receptor B2). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • B2 bradykinin receptor
  • B2R
  • BK-2 receptor
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Properties