| Protein Name | aminolevulinic acid synthase 2, erythroid |
|---|---|
| Organism | Mus musculus |
| Gene ID | 11656 |
| Gene Symbol | Alas2 |
| UniProt | P08680 (HEM0_MOUSE), A2AFM1 (A2AFM1_MOUSE), A2AFM0 (A2AFM0_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
33
Total Number of Articles : 29 |
Description |
aminolevulinic acid synthase 2, erythroid |
| Gene Summary |
Enables 5-aminolevulinate synthase activity. Involved in erythrocyte differentiation; heme biosynthetic process; and hemoglobin biosynthetic process. Acts upstream of or within intracellular iron ion homeostasis. Located in mitochondrion. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and liver and biliary system. Human ortholog(s) of this gene implicated in cutaneous porphyria; erythropoietic protoporphyria; hemochromatosis; sideroblastic anemia; and sideroblastic anemia 1. Orthologous to human ALAS2 (5'-aminolevulinate synthase 2). [provided by Alliance of Genome Resources, Jun 2025] |
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