Protein Name SLX4 structure-specific endonuclease subunit
Organism Homo sapiens
Gene ID 84464
Gene Symbol

SLX4

UniProt Q8IY92 (SLX4_HUMAN)
Relationships Total Number of functionally related compound(s) : 17
Total Number of Articles : 14
Description

SLX4 structure-specific endonuclease subunit

Gene Summary

This gene encodes a protein that functions as an assembly component of multiple structure-specific endonucleases. These endonuclease complexes are required for repair of specific types of DNA lesions and critical for cellular responses to replication fork failure. Mutations in this gene were found in patients with Fanconi anemia. [provided by RefSeq, Sep 2016]

synonyms
  • structure-specific endonuclease subunit SLX4
  • BTB/POZ domain-containing protein 12
  • BTBD12
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Properties