Protein Name hepcidin antimicrobial peptide 2
Organism Mus musculus
Gene ID 66438
Gene Symbol

Hamp2

UniProt Q80T19 (HEPC2_MOUSE)
Relationships Total Number of functionally related compound(s) : 3
Total Number of Articles : 6
Description

hepcidin antimicrobial peptide 2

Gene Summary

This gene encodes a peptide hormone that functions in the regulation of systemic iron metabolism. The encoded preproprotein is synthesized in the hepatocytes where it undergoes proteolytic processing to generate disulfide-linked mature peptides that are secreted into the bloodstream. Transgenic mice overexpressing the encoded protein develop normally with hematologic parameters similar to the non-transgenic mice. This gene is located adjacent to a related hepcidin gene on chromosome 7. [provided by RefSeq, Aug 2016]

synonyms
  • hepcidin-2
  • 1810073K19Rik
  • HEPC2
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Properties