| Protein Name | pellino 1 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 67245 |
| Gene Symbol | Peli1 |
| UniProt | Q8C669 (PELI1_MOUSE), Q5SRW7 (Q5SRW7_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
11
Total Number of Articles : 10 |
Description |
pellino 1 |
| Gene Summary |
Enables ubiquitin protein ligase activity. Involved in negative regulation of necroptotic process. Acts upstream of or within several processes, including positive regulation of signal transduction; regulation of lymphocyte proliferation; and regulation of macromolecule metabolic process. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; sensory organ; and skin. Human ortholog(s) of this gene implicated in colorectal cancer. Orthologous to human PELI1 (pellino E3 ubiquitin protein ligase 1). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |