Protein Name XIAP associated factor 1
Organism Homo sapiens
Gene ID 54739
Gene Symbol

XAF1

UniProt Q6GPH4 (XAF1_HUMAN)
Relationships Total Number of functionally related compound(s) : 34
Total Number of Articles : 42
Description

XIAP associated factor 1

Gene Summary

This gene encodes a protein which binds to and counteracts the inhibitory effect of a member of the IAP (inhibitor of apoptosis) protein family. IAP proteins bind to and inhibit caspases which are activated during apoptosis. The proportion of IAPs and proteins which interfere with their activity, such as the encoded protein, affect the progress of the apoptosis signaling pathway. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

synonyms
  • XIAP-associated factor 1
  • BIRC4-binding protein
  • BIRC4BP
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Properties