| Protein Name | eomesodermin |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 8320 |
| Gene Symbol | EOMES |
| UniProt | O95936 (EOMES_HUMAN), B7Z4K0 (B7Z4K0_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
33
Total Number of Articles : 28 |
Description |
eomesodermin |
| Gene Summary |
This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013] |
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| Properties | |