Protein Name proline, glutamate and leucine rich protein 1
Organism Homo sapiens
Gene ID 27043
Gene Symbol

PELP1

UniProt Q8IZL8 (PELP1_HUMAN), B4DEX7 (B4DEX7_HUMAN), B4DR36 (B4DR36_HUMAN), E7EV54 (E7EV54_HUMAN), C9JFV4 (C9JFV4_HUMAN)
Relationships Total Number of functionally related compound(s) : 41
Total Number of Articles : 60
Description

proline, glutamate and leucine rich protein 1

Gene Summary

This gene encodes a transcription factor which coactivates transcription of estrogen receptor responsive genes and corepresses genes activated by other hormone receptors or sequence-specific transcription factors. Expression of this gene is regulated by both members of the estrogen receptor family. This gene may be involved in the progression of several types of cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

synonyms
  • proline-, glutamic acid- and leucine-rich protein 1
  • modulator of non-genomic activity of estrogen receptor
  • proline and glutamic acid rich nuclear protein
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Properties