Protein Name reticulon 4
Organism Mus musculus
Gene ID 68585
Gene Symbol

Rtn4

UniProt Q99P72 (RTN4_MOUSE)
Relationships Total Number of functionally related compound(s) : 77
Total Number of Articles : 69
Description

reticulon 4

Gene Summary

Enables lipid binding activity. Involved in several processes, including positive regulation of intracellular signal transduction; positive regulation of leukocyte migration; and vasculogenesis. Acts upstream of or within blastocyst formation; cardiac epithelial to mesenchymal transition; and nervous system development. Located in cell projection; endoplasmic reticulum membrane; and postsynaptic density. Is active in glutamatergic synapse and postsynapse. Is expressed in several structures, including central nervous system; genitourinary system; limb mesenchyme; sensory organ; and skeletal musculature. Orthologous to human RTN4 (reticulon 4). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • reticulon-4
  • neurite outgrowth inhibitor
  • 1110020G17Rik
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Properties