| Protein Name | sepiapterin reductase |
|---|---|
| Organism | Mus musculus |
| Gene ID | 20751 |
| Gene Symbol | Spr |
| UniProt | Q91XH5 (Q91XH5_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
59
Total Number of Articles : 48 |
Description |
sepiapterin reductase |
| Gene Summary |
Enables protein homodimerization activity and sepiapterin reductase (NADP+) activity. Involved in tetrahydrobiopterin biosynthetic process. Acts upstream of or within several processes, including L-phenylalanine metabolic process; catecholamine metabolic process; and voluntary musculoskeletal movement. Located in mitochondrion. Is active in cytosol. Is expressed in several structures, including alimentary system; heart; nervous system; sensory organ; and skeleton. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in dystonia and sepiapterin reductase deficiency. Orthologous to human SPR (sepiapterin reductase). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |