Protein Name WD repeat domain 35
Organism Mus musculus
Gene ID 74682
Gene Symbol

Wdr35

UniProt Q8BND3 (WDR35_MOUSE)
Relationships Total Number of functionally related compound(s) : 10
Total Number of Articles : 5
Description

WD repeat domain 35

Gene Summary

Involved in cilium assembly. Acts upstream of or within cellular response to leukemia inhibitory factor. Located in axoneme; centrosome; and ciliary basal body. Part of intraciliary transport particle A. Is expressed in several structures, including choroid plexus; future forebrain; limb mesenchyme; lobar bronchus epithelium; and sensory organ. Used to study short-rib thoracic dysplasia 7 with or without polydactyly. Human ortholog(s) of this gene implicated in Ellis-Van Creveld syndrome; cranioectodermal dysplasia 2; and short-rib thoracic dysplasia 7 with or without polydactyly. Orthologous to human WDR35 (WD repeat domain 35). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • WD repeat-containing protein 35
  • 4930459M12Rik
  • 4931430C06
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Properties