Protein Name synaptotagmin I
Organism Mus musculus
Gene ID 20979
Gene Symbol

Syt1

UniProt P46096 (SYT1_MOUSE), H6RXZ1 (H6RXZ1_MOUSE)
Relationships Total Number of functionally related compound(s) : 62
Total Number of Articles : 62
Description

synaptotagmin I

Gene Summary

Enables several functions, including calcium ion sensor activity; calcium-dependent phospholipid binding activity; and syntaxin-1 binding activity. Involved in modulation of chemical synaptic transmission; regulation of dopamine secretion; and synaptic vesicle exocytosis. Acts upstream of or within calcium ion-regulated exocytosis of neurotransmitter; spontaneous neurotransmitter secretion; and synchronous neurotransmitter secretion. Located in several cellular components, including Golgi apparatus; presynaptic membrane; and secretory vesicle. Is active in glutamatergic synapse. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; peripheral nervous system ganglion; and sensory organ. Orthologous to human SYT1 (synaptotagmin 1). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • synaptotagmin-1
  • p65
  • G630098F17Rik
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Properties