CPRiL

Map2k7

mitogen-activated protein kinase kinase 7

Enables magnesium ion binding activity; protein kinase activity; and protein phosphatase binding activity. Involved in several processes, including JNK cascade; cellular response to lipopolysaccharide; and positive regulation of JNK cascade. Acts upstream of or within regulation of motor neuron apoptotic process and response to wounding. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; lung; musculoskeletal system; and sensory organ. Used to study schizophrenia. Human ortholog(s) of this gene implicated in colon adenocarcinoma; lung adenocarcinoma; lung carcinoma; and lung non-small cell carcinoma. Orthologous to human MAP2K7 (mitogen-activated protein kinase kinase 7). [provided by Alliance of Genome Resources, Jun 2025]

• dual specificity mitogen-activated protein kinase kinase 7
• JNK kinase 2
• JNK-activating kinase 2
MAP kinase kinase 7
MAPK/ERK kinase 7
c-Jun N-terminal kinase kinase 2
protein kinase, mitogen activated, kinase 7
5930412N11Rik
JNKK 2
Jnkk2
MAPKK 7
MEK 7
Mapkk7
Mek7
Mkk7
Prkmk7
sek2