CPRiL

USP21

ubiquitin specific peptidase 21

This gene encodes a member of the C19 peptidase family, also known as family 2 of ubiquitin carboxy-terminal hydrolases. The encoded protein cleaves ubiquitin from ubiquitinated proteins for recycling in intracellular protein degradation. The encoded protein is also able to release NEDD8, a ubiquitin-like protein, from NEDD8-conjugated proteins. This gene has been referred to as USP16 and USP23 but is now known as USP21. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]

• ubiquitin carboxyl-terminal hydrolase 21
• NEDD8-specific protease
• deubiquitinating enzyme 21
ubiquitin specific protease 21
ubiquitin thioesterase 21
ubiquitin thiolesterase 21
ubiquitin-specific processing protease 21
ubiquitin-specific protease 16
USP16
USP23