| Protein Name | vascular endothelial growth factor C |
|---|---|
| Organism | Mus musculus |
| Gene ID | 22341 |
| Gene Symbol | Vegfc |
| UniProt | P97953 (VEGFC_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
106
Total Number of Articles : 88 |
Description |
vascular endothelial growth factor C |
| Gene Summary |
Enables vascular endothelial growth factor receptor 3 binding activity. Involved in several processes, including negative regulation of osteoblast differentiation; positive regulation of lymphangiogenesis; and positive regulation of mesenchymal stem cell proliferation. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor; morphogenesis of embryonic epithelium; and positive regulation of glial cell proliferation. Located in extracellular space. Is expressed in several structures, including alimentary system mesentery; brain; cardiovascular system; embryo mesenchyme; and genitourinary system. Used to study hereditary lymphedema. Human ortholog(s) of this gene implicated in breast carcinoma and hereditary lymphedema ID. Orthologous to human VEGFC (vascular endothelial growth factor C). [provided by Alliance of Genome Resources, Jul 2025] |
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