Protein Name 3-phosphoglycerate dehydrogenase
Organism Mus musculus
Gene ID 236539
Gene Symbol

Phgdh

UniProt Q61753 (SERA_MOUSE)
Relationships Total Number of functionally related compound(s) : 51
Total Number of Articles : 58
Description

3-phosphoglycerate dehydrogenase

Gene Summary

Predicted to enable phosphoglycerate dehydrogenase activity. Acts upstream of or within several processes, including gamma-aminobutyric acid metabolic process; nervous system development; and proteinogenic amino acid metabolic process. Located in myelin sheath. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in Neu-Laxova syndrome 1; PHGDH deficiency; and amino acid metabolic disorder. Orthologous to human PHGDH (phosphoglycerate dehydrogenase). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • D-3-phosphoglycerate dehydrogenase
  • 3-phosphoglycerate dehyrogenase
  • 3-PGDH
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Properties