| Protein Name | hyperpolarization-activated, cyclic nucleotide-gated K+ 4 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 330953 |
| Gene Symbol | Hcn4 |
| UniProt | B2RY58 (B2RY58_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
36
Total Number of Articles : 52 |
Description |
hyperpolarization-activated, cyclic nucleotide-gated K+ 4 |
| Gene Summary |
Enables intracellularly cAMP-activated cation channel activity. Acts upstream of or within in utero embryonic development; monoatomic cation transport; and regulation of heart contraction. Located in axon. Is expressed in several structures, including eye; future brain; heart; septum transversum; and venous system. Human ortholog(s) of this gene implicated in Brugada syndrome 8; Gilles de la Tourette syndrome; generalized epilepsy; and sick sinus syndrome. Orthologous to human HCN4 (hyperpolarization activated cyclic nucleotide gated potassium channel 4). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |