Protein Name eukaryotic translation initiation factor 4A3
Organism Homo sapiens
Gene ID 9775
Gene Symbol

EIF4A3

UniProt P38919 (IF4A3_HUMAN), A0A024R8W0 (A0A024R8W0_HUMAN), I3L3H2 (I3L3H2_HUMAN)
Relationships Total Number of functionally related compound(s) : 35
Total Number of Articles : 32
Description

eukaryotic translation initiation factor 4A3

Gene Summary

This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a nuclear matrix protein. Its amino acid sequence is highly similar to the amino acid sequences of the translation initiation factors eIF4AI and eIF4AII, two other members of the DEAD box protein family. [provided by RefSeq, Jul 2008]

synonyms
  • eukaryotic initiation factor 4A-III
  • ATP-dependent RNA helicase DDX48
  • ATP-dependent RNA helicase eIF4A-3
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Properties