Protein Name amine oxidase copper containing 3
Organism Homo sapiens
Gene ID 8639
Gene Symbol

AOC3

UniProt Q16853 (AOC3_HUMAN), Q9UEU7 (Q9UEU7_HUMAN)
Relationships Total Number of functionally related compound(s) : 138
Total Number of Articles : 135
Description

amine oxidase copper containing 3

Gene Summary

This gene encodes a member of the semicarbazide-sensitive amine oxidase family. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The encoded protein is localized to the cell surface, has adhesive properties as well as monoamine oxidase activity, and may be involved in leukocyte trafficking. Alterations in levels of the encoded protein may be associated with many diseases, including diabetes mellitus. A pseudogene of this gene has been described and is located approximately 9-kb downstream on the same chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]

synonyms
  • amine oxidase [copper-containing] 3
  • membrane primary amine oxidase
  • amine oxidase, copper containing 3 (vascular adhesion protein 1)
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Properties