Protein Name Ly6/neurotoxin 1
Organism Homo sapiens
Gene ID 66004
Gene Symbol

LYNX1

UniProt P0DP58 (LYNX1_HUMAN)
Relationships Total Number of functionally related compound(s) : 14
Total Number of Articles : 20
Description

Ly6/neurotoxin 1

Gene Summary

This gene encodes a GPI-anchored, cell membrane bound member of the Ly6/uPAR (LU) superfamily of proteins containing the unique three-finger LU domain. This protein interacts with nicotinic acetylcholine receptors (nAChRs), and is thought to function as a modulator of nAChR activity to prevent excessive excitation. Alternatively spliced transcript variants have been found for this gene. Read-through transcription between this gene and the neighboring downstream gene (SLURP2) generates naturally-occurring transcripts (LYNX1-SLURP2) that encode a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Sep 2017]

synonyms
  • ly-6/neurotoxin-like protein 1
  • Ly-6 neurotoxin-like protein 1
  • endogenous prototoxin LYNX1
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Properties