Protein Name | Ly6/neurotoxin 1 |
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Organism | Homo sapiens |
Gene ID | 66004 |
Gene Symbol | LYNX1 |
UniProt | P0DP58 (LYNX1_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
14
Total Number of Articles : 20 |
Description |
Ly6/neurotoxin 1 |
Gene Summary |
This gene encodes a GPI-anchored, cell membrane bound member of the Ly6/uPAR (LU) superfamily of proteins containing the unique three-finger LU domain. This protein interacts with nicotinic acetylcholine receptors (nAChRs), and is thought to function as a modulator of nAChR activity to prevent excessive excitation. Alternatively spliced transcript variants have been found for this gene. Read-through transcription between this gene and the neighboring downstream gene (SLURP2) generates naturally-occurring transcripts (LYNX1-SLURP2) that encode a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Sep 2017] |
synonyms |
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Properties | |