Protein Name cell division cycle 42
Organism Rattus norvegicus
Gene ID 64465
Gene Symbol

Cdc42

UniProt Q8CFN2 (CDC42_RAT), A0A0G2JSM8 (A0A0G2JSM8_RAT)
Relationships Total Number of functionally related compound(s) : 86
Total Number of Articles : 91
Description

cell division cycle 42

Gene Summary

Enables GTP binding activity and mitogen-activated protein kinase kinase kinase binding activity. Involved in several processes, including actin filament branching; establishment of Golgi localization; and regulation of synapse organization. Located in Golgi membrane; plasma membrane; and secretory granule. Is active in Schaffer collateral - CA1 synapse. Biomarker of temporal lobe epilepsy. Human ortholog(s) of this gene implicated in fibrosarcoma. Orthologous to human CDC42 (cell division cycle 42). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • cell division control protein 42 homolog
  • cell division cycle 42 (GTP binding protein)
  • cell division cycle 42 homolog
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Properties