| Protein Name | interleukin 15 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 16168 |
| Gene Symbol | Il15 |
| UniProt | P48346 (IL15_MOUSE), Q3U1Z6 (Q3U1Z6_MOUSE), Q1AHQ6 (Q1AHQ6_MOUSE), Q1AHQ7 (Q1AHQ7_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
191
Total Number of Articles : 184 |
Description |
interleukin 15 |
| Gene Summary |
This gene encodes a a pleiotropic cytokine of the interleukin family of proteins that plays important roles in the innate and adaptive cell homeostasis, as well as peripheral immune function. The encoded protein undergoes proteolytic processing to generate a mature cytokine that stimulates the proliferation of natural killer cells. The transgenic mice overexpressing the encoded protein exhibit an increase in the number of memory CD8+ T cells in a naive state and enhanced protection against bacterial infections. Mice lacking the encoded protein exhibit impaired protection against a strain of attenuated Mycobacterium. [provided by RefSeq, Aug 2016] |
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