| Protein Name | DISC1 scaffold protein |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 27185 |
| Gene Symbol | DISC1 |
| UniProt | Q9NRI5 (DISC1_HUMAN), C4P0A5 (C4P0A5_HUMAN), C4P094 (C4P094_HUMAN), C4P0C4 (C4P0C4_HUMAN), C4P0D1 (C4P0D1_HUMAN), C4P0A4 (C4P0A4_HUMAN), C4P0C8 (C4P0C8_HUMAN), C4P0D0 (C4P0D0_HUMAN), C4P0D2 (C4P0D2_HUMAN), C4P0D3 (C4P0D3_HUMAN), C4P096 (C4P096_HUMAN), C4P098 (C4P098_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
53
Total Number of Articles : 79 |
Description |
DISC1 scaffold protein |
| Gene Summary |
This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
| synonyms |
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| Properties | |