Protein Name DISC1 scaffold protein
Organism Homo sapiens
Gene ID 27185
Gene Symbol


UniProt Q9NRI5 (DISC1_HUMAN), C4P0A5 (C4P0A5_HUMAN), C4P094 (C4P094_HUMAN), C4P0C4 (C4P0C4_HUMAN), C4P0D1 (C4P0D1_HUMAN), C4P0A4 (C4P0A4_HUMAN), C4P0C8 (C4P0C8_HUMAN), C4P0D0 (C4P0D0_HUMAN), C4P0D2 (C4P0D2_HUMAN), C4P0D3 (C4P0D3_HUMAN), C4P096 (C4P096_HUMAN), C4P098 (C4P098_HUMAN)
Relationships Total Number of functionally related compound(s) : 53
Total Number of Articles : 79

DISC1 scaffold protein

Gene Summary

This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

  • disrupted in schizophrenia 1 protein
  • C1orf136
  • SCZD9
Click to show/hide the synonyms