Protein Name C-C motif chemokine ligand 12
Organism Mus musculus
Gene ID 20293
Gene Symbol

Ccl12

UniProt Q62401 (CCL12_MOUSE), Q545B5 (Q545B5_MOUSE)
Relationships Total Number of functionally related compound(s) : 23
Total Number of Articles : 22
Description

C-C motif chemokine ligand 12

Gene Summary

Enables CCR2 chemokine receptor binding activity. Involved in angiogenesis; inflammatory response; and monocyte chemotaxis. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in central nervous system and retina. Human ortholog(s) of this gene implicated in several diseases, including IgA vasculitis; aggressive periodontitis; autoimmune disease (multiple); end stage renal disease; and gastrointestinal system cancer (multiple). Orthologous to several human genes including CCL2 (C-C motif chemokine ligand 2). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • C-C motif chemokine 12
  • MCP-1-related chemokine
  • chemokine (C-C motif) ligand 12
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Properties