Protein Name ATG5 autophagy related 5 homolog (S. cerevisiae)
Organism Danio rerio
Gene ID 494180
Gene Symbol

atg5

UniProt F1RDC0 (F1RDC0_DANRE)
Relationships Total Number of functionally related compound(s) : 6
Total Number of Articles : 5
Description

ATG5 autophagy related 5 homolog (S. cerevisiae)

Gene Summary

Predicted to contribute to Atg8-family ligase activity. Acts upstream of or within several processes, including autophagosome assembly; heart development; and regulation of skeletal muscle tissue regeneration. Predicted to be located in cytoplasm and membrane. Predicted to be part of Atg12-Atg5-Atg16 complex. Predicted to be active in autophagosome; phagophore; and phagophore assembly site membrane. Is expressed in several structures, including heart; liver; male organism; nervous system; and tail bud. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 25. Orthologous to human ATG5 (autophagy related 5). [provided by Alliance of Genome Resources, Apr 2025]

synonyms
  • autophagy protein 5
  • autophagy 5-like protein
  • apg5l
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Properties