Protein Name glycogen synthase kinase 3 beta, genome duplicate a
Organism Danio rerio
Gene ID 30654
Gene Symbol

gsk3ba

UniProt Q9YH60 (Q9YH60_DANRE)
Relationships Total Number of functionally related compound(s) : 45
Total Number of Articles : 36
Description

glycogen synthase kinase 3 beta, genome duplicate a

Gene Summary

Predicted to enable beta-catenin binding activity and tau-protein kinase activity. Involved in heart valve development. Acts upstream of or within angiogenesis; heart jogging; and heart looping. Predicted to be located in plasma membrane. Predicted to be part of beta-catenin destruction complex. Predicted to be active in several cellular components, including axon; cytosol; and glutamatergic synapse. Is expressed in liver; ovary; and testis. Human ortholog(s) of this gene implicated in Alzheimer's disease; amyotrophic lateral sclerosis; bipolar disorder; oral squamous cell carcinoma; and schizophrenia. Orthologous to human GSK3B (glycogen synthase kinase 3 beta). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • glycogen synthase kinase-3 beta
  • GSK-3[b]
  • GSK3
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Properties