Protein Name | glycogen synthase kinase 3 beta, genome duplicate a |
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Organism | Danio rerio |
Gene ID | 30654 |
Gene Symbol | gsk3ba |
UniProt | Q9YH60 (Q9YH60_DANRE) |
Relationships |
Total Number of functionally related compound(s) :
45
Total Number of Articles : 36 |
Description |
glycogen synthase kinase 3 beta, genome duplicate a |
Gene Summary |
Predicted to enable beta-catenin binding activity and tau-protein kinase activity. Involved in heart valve development. Acts upstream of or within angiogenesis; heart jogging; and heart looping. Predicted to be located in plasma membrane. Predicted to be part of beta-catenin destruction complex. Predicted to be active in several cellular components, including axon; cytosol; and glutamatergic synapse. Is expressed in liver; ovary; and testis. Human ortholog(s) of this gene implicated in Alzheimer's disease; amyotrophic lateral sclerosis; bipolar disorder; oral squamous cell carcinoma; and schizophrenia. Orthologous to human GSK3B (glycogen synthase kinase 3 beta). [provided by Alliance of Genome Resources, Jul 2025] |
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Properties | |