Protein Name chemokine (C-X-C motif) ligand 8a
Organism Danio rerio
Gene ID 100002946
Gene Symbol

cxcl8a

UniProt A0A0G2KYH9 (A0A0G2KYH9_DANRE)
Relationships Total Number of functionally related compound(s) : 32
Total Number of Articles : 25
Description

chemokine (C-X-C motif) ligand 8a

Gene Summary

Enables chemokine activity. Acts upstream of or within several processes, including blood vessel morphogenesis; endothelial to hematopoietic transition; and hematopoietic stem cell differentiation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including eye; heart; liver; pleuroperitoneal region; and ventral wall of dorsal aorta. Used to study vitamin D-dependent rickets. Human ortholog(s) of this gene implicated in several diseases, including acute pyelonephritis; autoimmune uveitis; gastritis (multiple); liver disease (multiple); and lung disease (multiple). Orthologous to human CXCL8 (C-X-C motif chemokine ligand 8). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • growth-regulated alpha protein
  • interleukin-8
  • CXCL8_L1_chr1
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Properties