Protein Name zinc finger protein, FOG family member 2
Organism Homo sapiens
Gene ID 23414
Gene Symbol

ZFPM2

UniProt Q8WW38 (FOG2_HUMAN), Q9NPQ0 (Q9NPQ0_HUMAN)
Relationships Total Number of functionally related compound(s) : 21
Total Number of Articles : 15
Description

zinc finger protein, FOG family member 2

Gene Summary

The zinc finger protein encoded by this gene is a widely expressed member of the FOG family of transcription factors. The family members modulate the activity of GATA family proteins, which are important regulators of hematopoiesis and cardiogenesis in mammals. It has been demonstrated that the protein can both activate and down-regulate expression of GATA-target genes, suggesting different modulation in different promoter contexts. A related mRNA suggests an alternatively spliced product but this information is not yet fully supported by the sequence. [provided by RefSeq, Jul 2008]

synonyms
  • zinc finger protein ZFPM2
  • FOG-2
  • Friend of GATA2
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Properties