Protein Name Processed sterol regulatory element binding protein sbp-1
Organism Caenorhabditis elegans
Gene ID 176574
Gene Symbol

sbp-1

UniProt Q9XX00 (Q9XX00_CAEEL)
Relationships Total Number of functionally related compound(s) : 25
Total Number of Articles : 20
Description

Processed sterol regulatory element binding protein sbp-1

Gene Summary

Enables DNA-binding transcription factor activity. Involved in several processes, including determination of adult lifespan; positive regulation of lipid storage; and response to anoxia. Located in nucleus. Is expressed in several structures, including head; intestine; and terminal bulb. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in carotid artery disease; disease of metabolism (multiple); prostate cancer; and vascular dementia. Orthologous to several human genes including SREBF2 (sterol regulatory element binding transcription factor 2). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • Processed sterol regulatory element binding protein sbp-1
  • CELE_Y47D3B.7
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Properties