Protein Name beta-transducin repeat containing E3 ubiquitin protein ligase
Organism Rattus norvegicus
Gene ID 361765
Gene Symbol

Btrc

UniProt F1LMH8 (F1LMH8_RAT), Q5U4E5 (Q5U4E5_RAT)
Relationships Total Number of functionally related compound(s) : 8
Total Number of Articles : 3
Description

beta-transducin repeat containing E3 ubiquitin protein ligase

Gene Summary

Predicted to enable several functions, including beta-catenin binding activity; ubiquitin ligase activator activity; and ubiquitin ligase-substrate adaptor activity. Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in several processes, including cellular protein metabolic process; positive regulation of nitrogen compound metabolic process; and protein destabilization. Predicted to act upstream of or within several processes, including mammary gland epithelium development; protein K48-linked ubiquitination; and regulation of I-kappaB kinase/NF-kappaB signaling. Predicted to be located in cytoplasm and nucleus. Predicted to be part of SCF ubiquitin ligase complex. Orthologous to human BTRC (beta-transducin repeat containing E3 ubiquitin protein ligase). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • F-box/WD repeat-containing protein 1A
  • beta-transducin repeat containing protein
  • beta-TrCP1
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Properties