Protein Name potassium inwardly-rectifying channel, subfamily J, member 10
Organism Rattus norvegicus
Gene ID 29718
Gene Symbol

Kcnj10

UniProt P49655 (KCJ10_RAT)
Relationships Total Number of functionally related compound(s) : 59
Total Number of Articles : 64
Description

potassium inwardly-rectifying channel, subfamily J, member 10

Gene Summary

Enables identical protein binding activity and signaling receptor binding activity. Involved in several processes, including membrane hyperpolarization; potassium ion import across plasma membrane; and response to corticosteroid. Located in several cellular components, including astrocyte projection; basolateral plasma membrane; and microvillus. Used to study diabetic retinopathy. Biomarker of amyotrophic lateral sclerosis; brain disease (multiple); eye disease (multiple); and sensorineural hearing loss. Human ortholog(s) of this gene implicated in EAST syndrome and autosomal recessive nonsyndromic deafness 4. Orthologous to human KCNJ10 (potassium inwardly rectifying channel subfamily J member 10). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • ATP-sensitive inward rectifier potassium channel 10
  • ATP-sensitive inward rectifier potassium channel KAB-2
  • BIR10
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Properties